Never hit this issue before with the 10 sites I've done or manage, the site I'm working on is done and currently sites in a subdirectory on my hosting account. Now that it is ready I have the domain setup and ready to go, I change the URL options and the site comes up but with the layout all wrong, it looks like it is missing the stylesheet.
I tried to hard code in the location of the stylesheet and that didn't work, any ideas?